Friday, March 23, 2012

These Molecular Sorting Machines Cooperate With Each Other in a “Complex Topology”

The mitochondria inner membrane has an army of protein machines that carry out the mitochondria’s job of constructing ATP molecules—the all-purpose cellular energy source. These proteins are specialized for specific tasks and are precisely arranged in the inner membrane environment. As one writer explained:

The generators in the cellular power plants are biological membranes located inside the mitochondria. Even minute errors in the composition of the inner mitochondrial membrane can lead to severe metabolic derangements, which can have an especially negative impact on the energy-hungry muscle and nerve cells. In order to function, the cellular generators depend on the support of numerous highly specialized membrane proteins in the inner mitochondrial membrane.

Not surprisingly, except to evolutionists, the machinery that transports and locates these protein machines is also highly complex. In fact, research is now indicating that at least two different sorting machines, using two different mechanisms, work in a cooperative and coordinated manner:

Stop-transfer and conservative sorting are not mutually exclusive pathways but represent sorting mechanisms that cooperate in the membrane integration of a protein with complex topology. We conclude that the multispanning protein is inserted in a modular manner by the coordinated action of two inner-membrane preprotein translocases.

Findings such as these are common in biology. Evolutionists misrepresent the biological world as a fluke that just happened to come together. They cannot explain how this is possible, but they insist it must be so. Within evolution there is a sort of militant advocacy that cannot tolerate even so much as minor doubts about whether evolution is true. It is perfectly acceptable to doubt the various sub hypotheses of evolution, but not evolution itself. This is because if evolution is not true, then all kinds of dogmatic convictions come into question. And so it is imperative for evolutionists to defend their theory at any cost, even if that includes casting scientific inquiry as nefarious, blackballing dissenters, misrepresenting science, and so forth. Of course most evolutionists would never think of their movement in such terms. Instead, evolution is viewed as “just science” and any doubt about evolution is viewed as religiously-motivated creationism. The truth is precisely the opposite.

14 comments:

  1. Here's a good video on it:

    Powering the Cell: Mitochondria - video
    http://www.youtube.com/watch?v=RrS2uROUjK4

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  2. Not surprisingly, except to evolutionists, the machinery that transports and locates these protein machines is also highly complex.

    I think complexity, in anything, is always surprising. But why would simplicity be expected from evolutionary theory, as you seem to imply? What are the grounds for your expectations of great complexity?

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  3. Here is a article of related interest:

    Your Rotary Engines Are Arranged in Factories - August 2011
    Excerpt: As if ATP synthase was not amazing enough, a team of scientists in Germany now tells us they are arranged in rows with other equipment to optimize performance. From electron micrographs of intact mitochondria, they were able to detect the rotary engines of ATP synthase and other parts of the respiratory chain. Their diagram in an open-source paper in PNAS looks for all the world like a factory.,,, “We propose that the supramolecular organization of respiratory chain complexes as proton sources and ATP synthase rows as proton sinks in the mitochondrial cristae ensures optimal conditions for efficient ATP synthesis.” The authors had virtually nothing to say about how this might have evolved, noting only that the structure is “conserved during evolution” in every sample they examined (3 species of fungi including yeast, potato, and mammal). What this means is a lack of evolution over nearly two billion years, in the standard evolutionary timeline.
    http://crev.info/content/110817-your_rotary_engines_are_arranged_in_factories

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  4. I think you should replace the word "evolutionists" with the word "naturalists."

    ReplyDelete
  5. There are an infinite number of universes and we just happen to exist in the one where everything assembled itself together through random processes.

    nothing to see here, move along...

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  6. Chance of the Gaps, eh, wgbutler777? This is called "blind faith". Just believe and move along.

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    Replies
    1. If you keep questioning my scientific conclusions I will start calling you nasty names and then try to get you fired from your job!

      Delete
    2. Sorry, but I don't work. I guess you can try to fire me from taking care of my kids or the household. Although, I'm trying to find where I called you a nasty name. Chance of the Gaps is the name of the explanation that skeptics use to try to explain things for which they do not have evidence for. They conclude that things must have occurred by chance, yet they have no proof, therefore, they have blind faith.

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    3. Also, are you implying that the skeptic's view should never be questioned, only the theist's view?

      Delete

    4. are you implying that the skeptic's view should never be questioned, only the theist's view?


      Yes, exactly! It's perfectly fine to have blind faith in things like unobservable infinite universes, primordial goo self-assembling into primitive lifeforms, bacteria eventually mutating into human beings, and consciousness arising from non-consciousness, but its sheer stupidity to think that there could be design to life and the universe!

      That's unscientific, and besides, it potentially makes me accountable to a higher power and means that I just can't live however I want!

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    5. Wg,
      All those things can be true and you still could be accountable to a higher power,just not to your particular favorite

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  7. Machinery, mechanisms, power plants, generators, specific arrangement of parts, transport, support and location devices...

    It's no longer simply Biology. MIT's Biological Engineering description of their field:

    http://web.mit.edu/be/index.shtml

    "Our departmental epigram is 'Creating Biological Technologies, from Discovery to Design', ... integrating molecular and cellular biosciences with a quantitative, systems-oriented engineering analysis and synthesis approach, ... BE also partners with the departments of Biology and Electrical Engineering & Computer Science to jointly offer a PhD in Computational & Systems Biology, and with the departments of Biology and Civil & Environmental Engineering ..."

    Crying anything less than design when observing the cell is akin to driving by a bridge or a power plant and crying chance.

    I think it's fair to say the landscape is changing.

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  8. Franck Barfety

    It's no longer simply Biology. MIT's Biological Engineering description of their field


    Why did you quote mine the crap the BE introductory statement and cut out all mention of what the program is really about?

    "The Department of Biological Engineering was founded in 1998 as a new MIT academic unit, with the mission of defining and establishing a new discipline fusing molecular life sciences with engineering. The goal of this biological engineering discipline is to advance fundamental understanding of how biological systems operate and to develop effective biology-based technologies for applications across a wide spectrum of societal needs including breakthroughs in diagnosis, treatment, and prevention of disease, in design of novel materials, devices, and processes, and in enhancing environmental health. Our departmental epigram is 'Creating Biological Technologies, from Discovery to Design', designating our intertwined emphases on advances in basic bioscience and in applied biotechnology. The innovative educational programs created by BE reflect this emphasis on integrating molecular and cellular biosciences with a quantitative, systems-oriented engineering analysis and synthesis approach, offering opportunities at the undergraduate level for the SB in Biological Engineering and at the graduate level for the PhD in either Applied Biosciences or Bioengineering. BE also partners with the departments of Biology and Electrical Engineering & Computer Science to jointly offer a PhD in Computational & Systems Biology, and with the departments of Biology and Civil & Environmental Engineering to jointly offer a PhD in Microbiology."

    The BE program is about integrating naturally occurring biological features into new human produced designs. It says nothing about the naturally found biological feature being themselves designed.

    I think it's fair to say the landscape is changing.

    I think it's fair to say yet another dishonest Intelligent Design Creationist crawled out from under his rock.

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    Replies
    1. Human DNA is like a computer program but far, far more advanced than any software we've ever created.
      Bill Gates, The Road Ahead, 1996, p. 188

      In fact, though the original site is down now, the year CoSBi came out, which Bill Gates funded, this is what they had on their header page:

      Welcome to CoSBi - (Computational and Systems Biology)
      Excerpt: Biological systems are the most parallel systems ever studied and we hope to use our better understanding of how living systems handle information to design new computational paradigms, programming languages and software development environments. The net result would be the design and implementation of better applications firmly grounded on new computational, massively parallel paradigms in many different areas.
      http://www.cosbi.eu/index.php/component/content/article/171

      notes:

      Do you believe Richard Dawkins exists?
      Excerpt: DNA is the best information storage mechanism known to man. A single pinhead of DNA contains as much information as could be stored on 2 million two-terabyte hard drives.
      http://creation.com/does-dawkins-exist


      The data compression of some stretches of human DNA is estimated to be up to 12 codes thick (12 different ways of DNA transcription) (Trifonov, 1989). (This is well beyond the complexity of any computer code ever written by man). John Sanford - Genetic Entropy

      The multiple codes of nucleotide sequences. Trifonov EN. - 1989
      Excerpt: Nucleotide sequences carry genetic information of many different kinds, not just instructions for protein synthesis (triplet code).
      http://www.ncbi.nlm.nih.gov/pubmed/2673451

      The coding system used for living beings is optimal from an engineering standpoint.
      Werner Gitt - In The Beginning Was Information - p. 95

      3-D Structure Of Human Genome: Fractal Globule Architecture Packs Two Meters Of DNA Into Each Cell - Oct. 2009
      Excerpt: the information density in the nucleus is trillions of times higher than on a computer chip -- while avoiding the knots and tangles that might interfere with the cell's ability to read its own genome. Moreover, the DNA can easily unfold and refold during gene activation, gene repression, and cell replication.
      http://www.sciencedaily.com/releases/2009/10/091008142957.htm

      "In the last ten years, at least 20 different natural information codes were discovered in life, each operating to arbitrary conventions (not determined by law or physicality). Examples include protein address codes [Ber08B], acetylation codes [Kni06], RNA codes [Fai07], metabolic codes [Bru07], cytoskeleton codes [Gim08], histone codes [Jen01], and alternative splicing codes [Bar10].
      Donald E. Johnson – Programming of Life – pg.51 - 2010

      etc.. etc.. etc..

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